To connect to Sage 300, you can use either a DSN or an ODBC connection string. Both of these methods use the Database's Open method.

Connect to a DSN

To connect using a DSN:

var db = new Database();
db.open("DSN=CData Sage300 Sys", (err) => {
    // Use the connection
});

Provide a Driver Connection String

To connect using an ODBC connection string:

var db = new Database();
db.open("DRIVER={CData ODBC Driver for Sage 300};User=SAMPLE;Password=password;URL=http://127.0.0.1/Sage300WebApi/v1/-/;Company=SAMINC;;", (err) => {
    // Use the connection
});