To connect to Microsoft Office 365, you can use either a DSN or an ODBC connection string. Both of these methods use the Database's Open method.

Connect to a DSN

To connect using a DSN:

var db = new Database();
db.open("DSN=CData Office365 Sys", (err) => {
    // Use the connection
});

Provide a Driver Connection String

To connect using an ODBC connection string:

var db = new Database();
db.open("DRIVER={CData ODBC Driver for Microsoft Office 365};OAuthClientId=MyApplicationId;OAuthClientSecret=MySecretKey;CallbackURL=http://localhost:33333;;", (err) => {
    // Use the connection
});