To connect to Sage 50 UK, you can use either a DSN or an ODBC connection string. Both of these methods use the Database's Open method.

Connect to a DSN

To connect using a DSN:

var db = new Database();
db.open("DSN=CData Sage50UK Sys", (err) => {
    // Use the connection
});

Provide a Driver Connection String

To connect using an ODBC connection string:

var db = new Database();
db.open("DRIVER={CData ODBC Driver for Sage 50 UK};URL=http://localhost:5493/sdata/accounts50/GCRM/{C4C863BE-B098-4A7D-A78B-D7A92B8ADB59};User=Manager;Password=xxxxxx;;", (err) => {
    // Use the connection
});